Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact

Acute myeloid leukaemia (AML) is characterised by phenotypic heterogeneity, which we hypothesise is a consequence of deregulated differentiation with transcriptional reminiscence of the normal compartment or cell-of-origin. Here, we propose a classification system based on normal myeloid progenitor...

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Veröffentlicht in:PLoS One
Hauptverfasser: Schönherz, Anna A., Bødker, Julie Støve, Schmitz, Alexander, Brøndum, Rasmus Froberg, Jakobsen, Lasse Hjort, Roug, Anne Stidsholt, Severinsen, Marianne T., El-Galaly, Tarec C., Jensen, Paw, Johnsen, Hans Erik, Bøgsted, Martin, Dybkær, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179860/
https://ncbi.nlm.nih.gov/pubmed/32324791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229593
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