Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice

Amino acids exert many biological functions, serving as allosteric regulators and neurotransmitters, as constituents in proteins and as nutrients. GCN2-mediated phosphorylation of eukaryotic initiation factor 2 alpha (elF2α) restores homeostasis in response to amino acid starvation (AAS) through the...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Yamazaki, Hiromi, Kasai, Shuya, Mimura, Junsei, Ye, Peng, Inose-Maruyama, Atsushi, Tanji, Kunikazu, Wakabayashi, Koichi, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Sato, Tsubasa, Ozaki, Taku, Cavener, Douglas R., Yamamoto, Masayuki, Itoh, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179835/
https://ncbi.nlm.nih.gov/pubmed/32324833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008693
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