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IRF3 and IRF8 Regulate NF-κB Signaling by Targeting MyD88 in Teleost Fish

MyD88 is a conserved intracellular adaptor, which plays an important role in the innate immune system. MyD88 transmits signals for downstream of toll-like and IL-1 receptors to activate NF-κB signaling pathway, which is tightly controlled in the immune response to maintain immune intensity and immun...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yan, Xiaolong, Zhao, Xueyan, Huo, Ruixuan, Xu, Tianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179762/
https://ncbi.nlm.nih.gov/pubmed/32373114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00606
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