Effects of Tenofovir on the Single-Dose Pharmacokinetics of Intravenous Morinidazole in Healthy Chinese Subjects

The effects of multiple-dose administration of tenofovir disoproxil fumarate (TDF) on the pharmacokinetics of morinidazole (MOR) were compared in healthy subjects. MOR exposure was similar, with an area under the curve from 0 h to infinity (AUC(0-∞)) treatment ratio for MOR+TDF/MOR of 1.01 (90% conf...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Wu, Guolan, Tang, Wenling, Lv, Duo, Wu, Lihua, Zhou, Huili, Yang, Xi, Zheng, Yunliang, Zhai, You, Shentu, Jianzhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179596/
https://ncbi.nlm.nih.gov/pubmed/32152080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02067-19
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