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Development of a Multiplex Real-Time PCR Assay for Rapid Detection of Tigecycline Resistance Gene tet(X) Variants from Bacterial, Fecal, and Environmental Samples

We developed a multiplex real-time SYBR green-based PCR assay for rapid detection of tet(X) and its variants, including tet(X1) and tet(X2) and high-level tigecycline resistance genes tet(X3), tet(X4), and tet(X5). We showed that the real-time PCR assay developed had high linearity (R(2) ≥ 0.996), s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Fu, Yulin, Liu, Dejun, Song, Huangwei, Liu, Zhihai, Jiang, Haiyang, Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179268/
https://ncbi.nlm.nih.gov/pubmed/32041710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02292-19
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