Novel 2,4-Disubstituted-1,3-Thiazole Derivatives: Synthesis, Anti-Candida Activity Evaluation and Interaction with Bovine Serum Albumine

Herein we report the synthesis of two novel series of 1,3-thiazole derivatives having a lipophilic C4-substituent on account of the increasing need for novel and versatile antifungal drugs for the treatment of resistant Candida sp.-based infections. Following their structural characterization, the a...

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Publicado no:Molecules
Main Authors: Pricopie, Andreea-Iulia, Focșan, Monica, Ionuț, Ioana, Marc, Gabriel, Vlase, Laurian, Găină, Luiza-Ioana, Vodnar, Dan C., Simon, Elemer, Barta, Gabriel, Pîrnău, Adrian, Oniga, Ovidiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179180/
https://ncbi.nlm.nih.gov/pubmed/32121062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25051079
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