Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-Like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents through the Modulation of SIRT6

3-iodothyronamine (T1AM) and the recently developed analog SG-2 are rapidly emerging as promising multi-target neuroprotective ligands able to reprogram lipid metabolism and to produce memory enhancement in mice. To elucidate the molecular mechanisms underlying the multi-target effects of these nove...

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Vydáno v:Molecules
Hlavní autoři: Bellusci, Lorenza, Runfola, Massimiliano, Carnicelli, Vittoria, Sestito, Simona, Fulceri, Federica, Santucci, Filippo, Lenzi, Paola, Fornai, Francesco, Rapposelli, Simona, Origlia, Nicola, Zucchi, Riccardo, Chiellini, Grazia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179148/
https://ncbi.nlm.nih.gov/pubmed/32110992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25051054
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