Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients with colorectal cancer

BACKGROUND: The human gut microbiome plays a critical role in the carcinogenesis of colorectal cancer (CRC). However, a comprehensive analysis of the interaction between the host and microbiome is still lacking. RESULTS: We found correlations between the change in abundance of microbial taxa, butyra...

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Udgivet i:BMC Microbiol
Main Authors: Wang, Qing, Ye, Jianzhong, Fang, Daiqiong, Lv, Longxian, Wu, Wenrui, Shi, Ding, Li, Yating, Yang, Liya, Bian, Xiaoyuan, Wu, Jingjing, Jiang, Xianwan, Wang, Kaicen, Wang, Qiangqiang, Hodson, Mark P., Thibaut, Loïc M., Ho, Joshua W. K., Giannoulatou, Eleni, Li, Lanjuan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178946/
https://ncbi.nlm.nih.gov/pubmed/32321427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-020-01762-2
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