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Causal network perturbations for instance-specific analysis of single cell and disease samples

MOTIVATION: Complex diseases involve perturbation in multiple pathways and a major challenge in clinical genomics is characterizing pathway perturbations in individual samples. This can lead to patient-specific identification of the underlying mechanism of disease thereby improving diagnosis and per...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Buschur, Kristina L, Chikina, Maria, Benos, Panayiotis V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178399/
https://ncbi.nlm.nih.gov/pubmed/31873725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz949
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