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Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity

Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon, is a group 1 carcinogen that introduces mutagenic DNA adducts into the genome. In this study, we investigated the molecular mechanisms underlying the involvement of silymarin in the reduction of DNA adduct formation by B[a]P-7,8-dihydrodiol-...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jee, Seung-Cheol, Kim, Min, Sung, Jung-Suk
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177818/
https://ncbi.nlm.nih.gov/pubmed/32235460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072369
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