Predominant Distribution of the RNAi Machinery at Apical Adherens Junctions in Colonic Epithelia Is Disrupted in Cancer

The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing complex (RISC). We recently reveale...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Nair-Menon, Joyce, Daulagala, Amanda C., Connor, Dean M., Rutledge, Lauren, Penix, Trevor, Bridges, Mary Catherine, Wellslager, Bridgette, Spyropoulos, Demetri D., Timmers, Cynthia D., Broome, Ann-Marie, Kourtidis, Antonis
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177752/
https://ncbi.nlm.nih.gov/pubmed/32272708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072559
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