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A Relatively Small Gradient of Extracellular pH Directs Migration of MDA-MB-231 Cells In Vitro

Hematogenous tumor metastasis begins with the invasion and spread of primary tumor cells in the local tissue leading to intravasation. We hypothesized that tumor cells might actively migrate toward intratumor vessels with the extracellular metabolic gradient acting as a guiding cue. Here, we determi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Takahashi, Eiji, Yamaguchi, Daisuke, Yamaoka, Yoshihisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177698/
https://ncbi.nlm.nih.gov/pubmed/32272744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072565
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