Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia

Protein tyrosine phosphatase receptor type γ (PTPRG) is a tumor suppressor gene, down-regulated in Chronic Myeloid Leukemia (CML) cells by the hypermethylation of its promoter region. β-catenin (CTNNB1) is a critical regulator of Leukemic Stem Cells (LSC) maintenance and CML proliferation. This stud...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Tomasello, Luisa, Vezzalini, Marzia, Boni, Christian, Bonifacio, Massimiliano, Scaffidi, Luigi, Yassin, Mohamed, Al-Dewik, Nader, Takam Kamga, Paul, Krampera, Mauro, Sorio, Claudio
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177637/
https://ncbi.nlm.nih.gov/pubmed/32225105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072298
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