Functional Analysis of IRF1 Reveals its Role in the Activation of the Type I IFN Pathway in Golden Pompano, Trachinotus ovatus (Linnaeus 1758)

Interferon (IFN) regulatory factor 1 (IRF1), a transcription factor with a novel helix–turn–helix DNA-binding domain, plays a crucial role in innate immunity by regulating the type I IFN signaling pathway. However, the regulatory mechanism through which IRF1 regulates type I IFN in fish is not yet e...

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Udgivet i:Int J Mol Sci
Main Authors: Zhu, Ke-Cheng, Zhang, Nan, Liu, Bao-Suo, Guo, Liang, Guo, Hua-Yang, Jiang, Shi-Gui, Zhang, Dian-Chang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177527/
https://ncbi.nlm.nih.gov/pubmed/32290244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072652
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