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Acute-on-chronic liver failure alters meropenem pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study

BACKGROUND: Infection and sepsis are a main cause of acute-on-chronic liver failure (ACLF). Adequate dosing of antimicrobial therapy is of central importance to improve outcome. Liver failure may alter antibiotic drug concentrations via changes of drug distribution and elimination. We studied the ph...

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Detalhes bibliográficos
Publicado no:Ann Intensive Care
Main Authors: Grensemann, Jörn, Busse, David, König, Christina, Roedl, Kevin, Jäger, Walter, Jarczak, Dominik, Iwersen-Bergmann, Stefanie, Manthey, Carolin, Kluge, Stefan, Kloft, Charlotte, Fuhrmann, Valentin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176801/
https://ncbi.nlm.nih.gov/pubmed/32323030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-020-00666-8
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