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Electrostatic Environment of Proteorhodopsin Affects the pKa of Its Buried Primary Proton Acceptor

The protonation state of embedded charged residues in transmembrane proteins (TMPs) can control the onset of protein function. It is understood that interactions between an embedded charged residue and other charged or polar residues in the moiety would influence its pKa, but how the surrounding env...

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Publicat a:Biophys J
Autors principals: Han, Chung-Ta, Song, Jichao, Chan, Tristan, Pruett, Christine, Han, Songi
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176579/
https://ncbi.nlm.nih.gov/pubmed/32197061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.02.027
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