Telomeres Increasingly Develop Aberrant Structures in Aging Humans

Telomeres progressively shorten with age, and it has been proposed that critically short and dysfunctional telomeres contribute to aging and aging-associated diseases in humans. For many years it was thought that telomere erosion was strictly a consequence of the “end replication problem,” or the in...

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Bibliografiske detaljer
Udgivet i:J Gerontol A Biol Sci Med Sci
Main Authors: Boccardi, Virginia, Cari, Luigi, Nocentini, Giuseppe, Riccardi, Carlo, Cecchetti, Roberta, Ruggiero, Carmelinda, Arosio, Beatrice, Paolisso, Giuseppe, Herbig, Utz, Mecocci, Patrizia
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176058/
https://ncbi.nlm.nih.gov/pubmed/30388200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly257
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