Nanomolar Potency Aminophenyltriazine CFTR Activator Reverses Corneal Epithelial Injury in a Mouse Model of Dry Eye

Purpose: Dry eye disorders are a major health care burden. We previously reported the identification of N-methyl-N-phenyl-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine [cystic fibrosis transmembrane conductance regulator (CFTR)(act)-K267], which activated human wild-type CFTR chloride co...

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Detalhes bibliográficos
Publicado no:J Ocul Pharmacol Ther
Main Authors: Chen, Xiaolan, Lee, Sujin, Zhang, Tianyi, Duan, Tianying, Pasricha, Neel D., Schallhorn, Julie M., Levin, Marc H., Koprivica, Vuk, Verkman, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175624/
https://ncbi.nlm.nih.gov/pubmed/31934802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2019.0087
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