Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

BACKGROUND: Robust activation of glial cells has been reported to occur particularly during the pathogenesis of bone cancer pain (BCP). Researchers from our group and others have shown that histone deacetylases (HDACs) play a significant role in modulating glia-mediated immune responses; however, it...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: He, Xiao-Tao, Hu, Xiao-Fan, Zhu, Chao, Zhou, Kai-Xiang, Zhao, Wen-Jun, Zhang, Chen, Han, Xiao, Wu, Chang-Le, Wei, Yan-Yan, Wang, Wei, Deng, Jian-Ping, Chen, Fa-Ming, Gu, Ze-Xu, Dong, Yu-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175547/
https://ncbi.nlm.nih.gov/pubmed/32321538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01740-5
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