A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse

BACKGROUND: Chronic neuroinflammation, aggressive amyloid beta (Aβ) deposition, neuronal cell loss, and cognitive impairment are pathological presentations of Alzheimer’s disease (AD). Therefore, resolution of neuroinflammation and inhibition of Aβ-driven pathology have been suggested to be importan...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Gee, Min Sung, Son, Seung Hwan, Jeon, Seung Ho, Do, Jimin, Kim, Namkwon, Ju, Yeon-Joo, Lee, Soo Jin, Chung, Eun Kyoung, Inn, Kyung-Soo, Kim, Nam-Jung, Lee, Jong Kil
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175487/
https://ncbi.nlm.nih.gov/pubmed/32317025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00617-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados