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Consistency of the Tools That Predict the Impact of Single Nucleotide Variants (SNVs) on Gene Functionality: The BRCA1 Gene

Single nucleotide variants (SNVs) occurring in a protein coding gene may disrupt its function in multiple ways. Predicting this disruption has been recognized as an important problem in bioinformatics research. Many tools, hereafter p-tools, have been designed to perform these predictions and many o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Murillo, Javier, Spetale, Flavio, Guillaume, Serge, Bulacio, Pilar, Garcia Labari, Ignacio, Cailloux, Olivier, Destercke, Sebastien, Tapia, Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175253/
https://ncbi.nlm.nih.gov/pubmed/32244891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030475
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