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Evaluation of the Safety and Efficacy of Avacopan, a C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Treated Concomitantly With Rituximab or Cyclophosphamide/Azathioprine: Protocol for a Randomized, Double-Blind, Active-Controlled, Phase 3 Trial

BACKGROUND: Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a serious, often life-threatening disease. In new-onset disease or a relapse, the standard treatment is immunosuppressive therapy with glucocorticoids; these therapies are associated with substantial short- and long-term...

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Detalhes bibliográficos
Publicado no:JMIR Res Protoc
Main Authors: Merkel, Peter A, Jayne, David R, Wang, Chao, Hillson, Jan, Bekker, Pirow
Formato: Artigo
Idioma:Inglês
Publicado em: JMIR Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175182/
https://ncbi.nlm.nih.gov/pubmed/32088663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2196/16664
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