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Fluorogenic and Bioorthogonal Modification of RNA Using Photoclick Chemistry

A bromoaryltetrazole-modified uridine was synthesized as a new RNA building block for bioorthogonal, light-activated and postsynthetic modification with commercially available fluorescent dyes. It allows “photoclick”-type modifications by irradiation with light (300 nm LED) at internal and terminal...

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Publicat a:Biomolecules
Autors principals: Krell, Katja, Wagenknecht, Hans-Achim
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175119/
https://ncbi.nlm.nih.gov/pubmed/32245224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030480
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