Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

BACKGROUND: SARS-CoV-2 is a RNA coronavirus responsible for the pandemic of the Severe Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation rate, up to a million times higher than that of their hosts. Virus mutagenic capability depends upon several factors, includi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Pachetti, Maria, Marini, Bruna, Benedetti, Francesca, Giudici, Fabiola, Mauro, Elisabetta, Storici, Paola, Masciovecchio, Claudio, Angeletti, Silvia, Ciccozzi, Massimo, Gallo, Robert C., Zella, Davide, Ippodrino, Rudy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174922/
https://ncbi.nlm.nih.gov/pubmed/32321524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02344-6
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