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Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic Acid Targets

Beyond its extraordinary genome editing ability, the CRISPR-Cas system has opened a new era of biosensing applications due to its high base resolution and isothermal signal amplification. However, the reported CRISPR-Cas sensors are largely only used for the detection of nucleic acids with limited a...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Xiong, Ying, Zhang, Jingjing, Yang, Zhenglin, Mou, Quanbing, Ma, Yuan, Xiong, Yonghua, Lu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174832/
https://ncbi.nlm.nih.gov/pubmed/31800219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09211
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