Pre-clinical Mouse Models of Neurodegenerative Lysosomal Storage Diseases

There are over 50 lysosomal hydrolase deficiencies, many of which cause neurodegeneration, cognitive decline and death. In recent years, a number of broad innovative therapies have been proposed and investigated for lysosomal storage diseases (LSDs), such as enzyme replacement, substrate reduction,...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Favret, Jacob M., Weinstock, Nadav I., Feltri, M. Laura, Shin, Daesung
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174556/
https://ncbi.nlm.nih.gov/pubmed/32351971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00057
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