Neoadjuvant PROSTVAC prior to radical prostatectomy enhances T-cell infiltration into the tumor immune microenvironment in men with prostate cancer

BACKGROUND: Clinical trials have shown the ability of therapeutic vaccines to generate immune responses to tumor-associated antigens (TAAs). What is relatively less known is if this translates into immune-cell (IC) infiltration into the tumor microenvironment. This study examined whether neoadjuvant...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Abdul Sater, Houssein, Marté, Jennifer L, Donahue, Renee N, Walter-Rodriguez, Beatriz, Heery, Christopher R, Steinberg, Seth M, Cordes, Lisa M, Chun, Guinevere, Karzai, Fatima, Bilusic, Marijo, Harmon, Stephanie A, Turkbey, Ismail Baris, Choyke, Peter L, Schlom, Jeffrey, Dahut, William L, Madan, Ravi A, Pinto, Peter A, Gulley, James L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174144/
https://ncbi.nlm.nih.gov/pubmed/32269146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000655
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