The long pentraxin PTX3 contributes to joint inflammation in gout by facilitating the phagocytosis of MSU crystals

OBJECTIVE: We aimed to investigate the role of pentraxin 3 (PTX3), a pivotal component of the innate immune system, in gout. METHODS: Two different cohorts of gout patients were investigated. A murine model of acute gout was induced by injection of monosodium urate (MSU) crystals in wild type mice a...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Batista, Nathália Vieira, Barbagallo, Marialuisa, Oliveira, Vivian Louise Soares, Oliveira, Rene Donizeti Ribeiro, Louzada-Junior, Paulo, Pinheiro, Geraldo da Rocha Castelar, Mantovani, Alberto, Teixeira, Mauro Martins, Garlanda, Cecilia, Amaral, Flávio Almeida
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174021/
https://ncbi.nlm.nih.gov/pubmed/30718300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701531
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