Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength

The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice were treated with a myostatin antibody while housed...

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Udgivet i:PLoS One
Main Authors: Smith, Rosamund C., Cramer, Martin S., Mitchell, Pamela J., Lucchesi, Jonathan, Ortega, Alicia M., Livingston, Eric W., Ballard, Darryl, Zhang, Ling, Hanson, Jeff, Barton, Kenneth, Berens, Shawn, Credille, Kelly M., Bateman, Ted A., Ferguson, Virginia L., Ma, Yanfei L., Stodieck, Louis S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173869/
https://ncbi.nlm.nih.gov/pubmed/32315311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230818
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