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Functional Circularity of Legitimate Qβ Replicase Templates

Qβ replicase (RNA-directed RNA polymerase of bacteriophage Qβ) exponentially amplifies certain RNAs in vitro. Previous studies have shown that Qβ replicase can initiate and elongate on a variety of RNAs; however, only a minute fraction of them are recognized as ‘legitimate’ templates. Guanosine 5′-t...

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書目詳細資料
發表在:J Mol Biol
Main Authors: Ugarov, Victor I., Chetverin, Alexander B.
格式: Artigo
語言:Inglês
出版: Elsevier Ltd. 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173182/
https://ncbi.nlm.nih.gov/pubmed/18466922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.03.074
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