Agonist and antagonist ligands of toll-like receptors 7 and 8: Ingenious tools for therapeutic purposes

The discovery of the TLRs family and more precisely its functions opened a variety of gates to modulate immunological host responses. TLRs 7/8 are located in the endosomal compartment and activate a specific signaling pathway in a MyD88-dependant manner. According to their involvement into various a...

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Dades bibliogràfiques
Publicat a:Eur J Med Chem
Autors principals: Patinote, Cindy, Karroum, Nour Bou, Moarbess, Georges, Cirnat, Natalina, Kassab, Issam, Bonnet, Pierre-Antoine, Deleuze-Masquéfa, Carine
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Masson SAS. 2020
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173040/
https://ncbi.nlm.nih.gov/pubmed/32203790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112238
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