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Development of a real-time RT-PCR assay for detection of resistance to oseltamivir in influenza A pandemic (H1N1) 2009 virus using single nucleotide polymorphism probes

Resistance to oseltamivir in pandemic (H1N1) 2009 influenza A virus is linked to an amino acid change from histidine (H) to tyrosine (Y) at position 275 in the neuraminidase protein (NA). A real-time one step RT-PCR assay using single nucleotide polymorphism (SNP) probes was developed to detect this...

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Publicado en:J Virol Methods
Autores principales: Wong, Sallene, Pabbaraju, Kanti, Wong, Anita, Fonseca, Kevin, Drews, Steven J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier B.V. 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172924/
https://ncbi.nlm.nih.gov/pubmed/21349290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2011.02.014
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