Efficacy of oral amoxicillin–clavulanate or azithromycin for non-severe respiratory exacerbations in children with bronchiectasis (BEST-1): a multicentre, three-arm, double-blind, randomised placebo-controlled trial

BACKGROUND: Bronchiectasis guidelines recommend antibiotics for the treatment of acute respiratory exacerbations, but randomised placebo-controlled trials in children are lacking. We hypothesised that oral amoxicillin–clavulanate and azithromycin would each be superior to placebo in achieving sympto...

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Detalhes bibliográficos
Publicado no:Lancet Respir Med
Main Authors: Goyal, Vikas, Grimwood, Keith, Ware, Robert S, Byrnes, Catherine A, Morris, Peter S, Masters, I Brent, McCallum, Gabrielle B, Binks, Michael J, Smith-Vaughan, Heidi, O'Grady, Kerry-Ann F, Champion, Anita, Buntain, Helen M, Schultz, André, Chatfield, Mark, Torzillo, Paul J, Chang, Anne B
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7172658/
https://ncbi.nlm.nih.gov/pubmed/31427252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(19)30254-1
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