A Validated RP-HPLC Stability Method for the Estimation of Chlorthalidone and Its Process-Related Impurities in an API and Tablet Formulation

Low-dose thiazide and thiazide-like diuretics are widely used as first-line therapy for hypertension. Chlorthalidone, a monosulfamyl diuretic, is frequently prescribed in cases of hypertension and congestive heart failure. In this research paper, an improved reverse-phase HPLC method was developed f...

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Publicat a:Int J Anal Chem
Autors principals: Kharat, Chaitali, Shirsat, Vaishali A., Kodgule, Yogita M., Kodgule, Mandar
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171635/
https://ncbi.nlm.nih.gov/pubmed/32328101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3593805
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