Stable Isotope-Assisted Metabolomics for Deciphering Xenobiotic Metabolism in Mammalian Cell Culture

[Image: see text] Xenobiotics are ubiquitous in the environment and modified in the human body by phase I and II metabolism. Liquid chromatography coupled to high resolution mass spectrometry is a powerful tool to investigate these biotransformation products. We present a workflow based on stable is...

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Библиографические подробности
Опубликовано в: :ACS Chem Biol
Главные авторы: Flasch, Mira, Bueschl, Christoph, Woelflingseder, Lydia, Schwartz-Zimmermann, Heidi E., Adam, Gerhard, Schuhmacher, Rainer, Marko, Doris, Warth, Benedikt
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2020
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171601/
https://ncbi.nlm.nih.gov/pubmed/32167285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b01016
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