EVALUATION OF ANDROGEN ASSAY RESULTS USING A CURATED HERSHBERGER DATABASE

A set of 39 reference chemicals with reproducible androgen pathway effects in vivo, identified in the companion manuscript [1], were used to interrogate the performance of the ToxCast/Tox 21 androgen receptor (AR) model based on 11 high throughput assays. Cytotoxicity data and specificity confirmati...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Kleinstreuer, NC, Browne, P, Chang, X, Judson, R, Casey, W, Ceger, P, Deisenroth, C, Baker, N, Markey, K, Thomas, RS
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171594/
https://ncbi.nlm.nih.gov/pubmed/30205137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2018.08.017
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