Reversal of HER2 Negativity: An Unexpected Role for Lovastatin in Triple-Negative Breast Cancer Stem Cells

Effective treatment modality for triple-negative breast cancer (TNBC) is currently lacking due to the absence of defined receptor targets. Recently, we have demonstrated that lovastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor and a lipid-lowering drug, can selectively inhibit TN...

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Podrobná bibliografie
Vydáno v:J Cancer
Hlavní autoři: Yi, Huimei, Wu, Mi, Zhang, Qiuting, Lu, Lu, Yao, Hui, Chen, Sisi, Li, Ying, Zheng, Chanjuan, He, Guangchun, Deng, Xiyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2020
Témata:
Short Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171481/
https://ncbi.nlm.nih.gov/pubmed/32328175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.39265
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