Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C

A central and unique aspect of high-grade serous ovarian carcinoma (HGSC) is the extensive transcoelomic spreading of tumor cell via the peritoneal fluid or malignant ascites. We and others identified tumor-associated macrophages (TAM) in the ascites as promoters of metastasis-associated processes l...

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Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Steitz, Anna Mary, Steffes, Alina, Finkernagel, Florian, Unger, Annika, Sommerfeld, Leah, Jansen, Julia M., Wagner, Uwe, Graumann, Johannes, Müller, Rolf, Reinartz, Silke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171168/
https://ncbi.nlm.nih.gov/pubmed/32312959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2438-8
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