Virtual biopsy using MRI radiomics for prediction of BRAF status in melanoma brain metastasis

Brain metastases are common in patients with advanced melanoma and constitute a major cause of morbidity and mortality. Between 40% and 60% of melanomas harbor BRAF mutations. Selective BRAF inhibitor therapy has yielded improvement in clinical outcome; however, genetic discordance between the prima...

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Udgivet i:Sci Rep
Main Authors: Shofty, Ben, Artzi, Moran, Shtrozberg, Shai, Fanizzi, Claudia, DiMeco, Francesco, Haim, Oz, Peleg Hason, Shira, Ram, Zvi, Bashat, Dafna Ben, Grossman, Rachel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170839/
https://ncbi.nlm.nih.gov/pubmed/32313236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63821-y
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