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A molecular view on the escape of lipoplexed DNA from the endosome
The use of non-viral vectors for in vivo gene therapy could drastically increase safety, whilst reducing the cost of preparing the vectors. A promising approach to non-viral vectors makes use of DNA/cationic liposome complexes (lipoplexes) to deliver the genetic material. Here we use coarse-grained...
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| Publicado en: | eLife |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7170654/ https://ncbi.nlm.nih.gov/pubmed/32297853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52012 |
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