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Therapeutic Potential of Ixekizumab in the Treatment of Ankylosing Spondylitis: A Review on the Emerging Clinical Data

Over the last 20 years, the greatly improved knowledges of underlying pathogenic mechanisms of AS, including the role of tumor necrosis factor (TNF), the interleukin 23/Th17 axis, and interleukin-17 (Il-17), constituted the rationale to develop biologics selectively inhibiting these pathways. For mo...

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Dettagli Bibliografici
Pubblicato in:Ther Clin Risk Manag
Autori principali: Benucci, Maurizio, Damiani, Arianna, Li Gobbi, Francesca, Grossi, Valentina, Infantino, Maria, Manfredi, Mariangela, Niccoli, Laura, Cantini, Fabrizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170548/
https://ncbi.nlm.nih.gov/pubmed/32368068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S228880
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