Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact

Following its evoked release, dopamine (DA) signaling is rapidly terminated by presynaptic reuptake, mediated by the cocaine-sensitive DA transporter (DAT). DAT surface availability is dynamically regulated by endocytic trafficking, and direct protein kinase C (PKC) activation acutely diminishes DAT...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Fagan, Rita R., Kearney, Patrick J., Sweeney, Carolyn G., Luethi, Dino, Schoot Uiterkamp, Florianne E., Schicker, Klaus, Alejandro, Brian S., O'Connor, Lauren C., Sitte, Harald H., Melikian, Haley E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170531/
https://ncbi.nlm.nih.gov/pubmed/32132171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012628
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