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Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis
Thermogenesis in brown adipose tissue (BAT) declines with age; however, what regulates this process remains poorly understood. Here, we identify mitochondria lipoylation as a previously unappreciated molecular hallmark of aged BAT in mice. Using mitochondrial proteomics, we show that mitochondrial l...
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| 出版年: | Nat Metab |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7169975/ https://ncbi.nlm.nih.gov/pubmed/32313871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0106-z |
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