Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis

The restrictive nature of the blood-brain barrier (BBB) creates a major challenge for brain drug delivery with current nanomedicines lacking the ability to cross the BBB. Extracellular vesicles (EVs) have been shown to contribute to the progression of a variety of brain diseases including metastatic...

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Bibliographic Details
Published in:ACS Nano
Main Authors: Morad, Golnaz, Carman, Christopher V., Hagedorn, Elliott J., Perlin, Julie R., Zon, Leonard I., Mustafaoglu, Nur, Park, Tae-Eun, Ingber, Donald E., Daisy, Cassandra C., Moses, Marsha A.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169949/
https://ncbi.nlm.nih.gov/pubmed/31479239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b04397
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