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Citrullinated Proteins in Arthritis; their Presence in Joints and Effects on Immunogenicity

Autoantibodies directed against citrulline‐containing proteins have an impressive specificity of nearly 100% in RA patients and a suggestive involvement in the pathogenesis. The targeted epitopes are generated by a post‐translational modification catalysed by the calcium‐dependent enzyme peptidyl ar...

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Detalhes bibliográficos
Publicado no:Scand J Immunol
Main Authors: Lundberg, K., Nijenhuis, S., Vossenaar, E., Venrooij, W. J., Klareskog, L., Harris, H. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd/Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169491/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0300-9475.2004.01423g.x
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