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Promoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line

BACKGROUND: Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major cause of Merkel cell carcinoma (MCC), an aggressive skin cancer. Se...

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Detalles Bibliográficos
Publicado en:Virol J
Main Authors: Abdulsalam, Ibrahim, Rasheed, Kashif, Sveinbjørnsson, Baldur, Ehlers, Bernhard, Moens, Ugo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168875/
https://ncbi.nlm.nih.gov/pubmed/32306957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01317-x
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