A comprehensive analysis of nuclear-encoded mitochondrial genes in schizophrenia

BACKGROUND: The genetic risk factors of schizophrenia (SCZ), a severe psychiatric disorder, are not yet fully understood. Multiple lines of evidence suggest mitochondrial dysfunction may play a role in SCZ, but comprehensive association studies are lacking. We hypothesized that variants in nuclear-e...

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Pubblicato in:Biol Psychiatry
Autori principali: Gonçalves, Vanessa F, Cappi, Carolina, Hagen, Christian M, Sequeira, Adolfo, Vawter, Marquis P, Derkach, Andriy, Zai, Clement C, Hedley, Paula L, Bybjerg-Grauholm, Jonas, Pouget, Jennie G, Cuperfain, Ari B., Sullivan, Patrick F, Christiansen, Michael, Kennedy, James L, Sun, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168759/
https://ncbi.nlm.nih.gov/pubmed/29628042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.02.1175
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