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Membrane Binding, Cellular Cholesterol Content and Resealing Capacity Contribute to Epithelial Cell Damage Induced by Suilysin of Streptococcus suis

Streptococcus (S.) suis is a major cause of economic losses in the pig industry worldwide and is an emerging zoonotic pathogen. One important virulence-associated factor is suilysin (SLY), a toxin that belongs to the family of cholesterol-dependent pore-forming cytolysins (CDC). However, the precise...

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Detalhes bibliográficos
Publicado no:Pathogens
Main Authors: Vötsch, Désirée, Willenborg, Maren, Oelemann, Walter M.R., Brogden, Graham, Valentin-Weigand, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168673/
https://ncbi.nlm.nih.gov/pubmed/31905867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9010033
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