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Chloroquine interferes with dengue‐2 virus replication in U937 cells

The objective of this study was to investigate the use of chloroquine (CLQ) as an antiviral agent against dengue. Chloroquine, an amine acidotropic drug known to affect intracellular exocytic pathways by increasing endosomal pH, was used in the in vitro treatment of U937 cells infected with dengue v...

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Bibliografiske detaljer
Udgivet i:Microbiol Immunol
Main Authors: Farias, Kleber Juvenal Silva, Machado, Paula Renata Lima, de Almeida Junior, Renato Ferreira, de Aquino, Ana Alice, da Fonseca, Benedito Antônio Lopes
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168487/
https://ncbi.nlm.nih.gov/pubmed/24773578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1348-0421.12154
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