Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV

Chelerythrine, sanguinarine and an alkaloid extract from Macleaya cordata—sanguiritrin—were found to be inhibitors of aminopeptidase A and dipeptidyl peptidase IV, while fagaronine inhibited dipeptidyl peptidase IV only. At 50 μm, chelerythrine, sanguinarine and sanguiritrin inhibited aminopeptidase...

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Bibliografiske detaljer
Udgivet i:Phytother Res
Main Authors: Šedo, Aleksi, Vlašicová, Květoslava, Barták, Petr, Vespalec, Radim, Vičar, Jaroslav, Šimánek, Vilim, Ulrichová, Jitka
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd. 2002
Fag:
Short Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168101/
https://ncbi.nlm.nih.gov/pubmed/11807974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ptr.969
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